Details for gene set CL17474, PHOSPHATIDYLINOSITOL 3-KINASE COMPLEX, CLASS I, AND INSULIN RECEPTOR COMPLEX[GSEA]

Table: GSEA Results Summary

Dataset	Medication for pain relief, constipation, heartburn__6154-both_sexes-4
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_pos
GeneSet	CL17474, PHOSPHATIDYLINOSITOL 3-KINASE COMPLEX, CLASS I, AND INSULIN RECEPTOR COMPLEX
Enrichment Score (ES)	0.60693187
Normalized Enrichment Score (NES)	1.2158586
Nominal p-value	0.14156626
FDR q-value	0.4003192
FWER p-Value	0.97

Fig 1: Enrichment plot: CL17474, PHOSPHATIDYLINOSITOL 3-KINASE COMPLEX, CLASS I, AND INSULIN RECEPTOR COMPLEX
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]
	SYMBOL	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PIK3R2	300	1.980	0.2172	Yes
2	IGF1R	433	1.778	0.4199	Yes
3	PIK3R6	567	1.646	0.6069	Yes
4	INSR	3119	0.681	0.5462	No
5	PIK3CA	3531	0.617	0.5962	No
6	PIK3CB	6295	0.351	0.4847	No
7	SOCS4	7066	0.303	0.4779	No
8	IRS2	8806	0.220	0.4077	No
9	PIK3CD	11000	0.148	0.3038	No
10	INSRR	11206	0.142	0.3092	No
11	PIK3R1	11551	0.132	0.3058	No
12	PIK3CG	12738	0.105	0.2525	No
13	IRS1	13213	0.095	0.2374	No
14	IRS4	13953	0.081	0.2061	No
15	PIK3R3	14066	0.079	0.2092	No
16	PTPN1	15030	0.063	0.1633	No
17	INS	15914	0.048	0.1201	No
18	PIK3R5	17146	-0.000	0.0519	No

Fig 2: CL17474, PHOSPHATIDYLINOSITOL 3-KINASE COMPLEX, CLASS I, AND INSULIN RECEPTOR COMPLEX: Random ES distribution
Gene set null distribution of ES for CL17474, PHOSPHATIDYLINOSITOL 3-KINASE COMPLEX, CLASS I, AND INSULIN RECEPTOR COMPLEX